Cane River is a 35-mile long lake formed from a portion of the Red River that is located in Natchitoches Parish, Louisiana. In the 19th and 20th centuries, it has been best known as the site of a historic Creole de couleur [1] (multiracial) culture that has centers upon the National Historic Landmark Melrose Plantation and nearby St. Augustine Church St. Augustine Parish (Isle Brevelle) Church.